S. aureus Penicillin Binding Protein: allosteric binding site and modulation of catalytic site

This paper describes existence of an allosteric site that also binds to b-lactams and modulates the binding of second b-lactam molecule at the catalytic site. Click here.
Authors: J Fishovitz, N Taghizadeh, JF Fisher, M Chang, and S Mobashery.
Here are two additional papers from preceding this. Click here and here.